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Cat. No.: HY-181994

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RNAP-IN-1

RNAP-IN-1 is a ribonucleic acid polymerase (RNAP) inhibitor, with an IC₅₀ of 0.95 μM against E. coli RNAP. RNAP-IN-1 can be used in studies of bacterial infections.

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Formule: C₂₂H₂₇N₇O₈
Masse moléculaire:517.49

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

RNAP-IN-1 Chemical Structure

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

RNAP-IN-1 is a ribonucleic acid polymerase (RNAP) inhibitor, with an IC₅₀ of 0.95 μM against E. coli RNAP. RNAP-IN-1 can be used in studies of bacterial infections^[1].

Voir tous les produits spécifiques à Isoform DNA/RNA Synthesis :

In Vitro

RNAP-IN-1 (Compound 54) potently inhibits purified Escherichia coli RNA polymerase (RNAP), with an IC₅₀ of 0.95 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

Masse moléculaire 517.49
Formule C₂₂H₂₇N₇O₈
SMILES

O[C@H]1[C@@H](O)[C@H](C(C(N2)=O)=CNC2=O)O[C@@H]1CNC([C@H](CCC(N)=O)NC(C3=CC=C(C(N)=N)C=C3)=O)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Anwar AF, et al. Solid-phase synthesis and biological evaluation of des-hydroxy pseudouridimycin analogs. ACS Med Chem Lett. Published online March 11, 2026. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Activité biologique
- Description
- In Vitro
Chemical Information
Pureté et documentation
Références

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RNAP-IN-1

Voir tous les produits spécifiques à Isoform DNA/RNA Synthesis

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

RNAP-IN-1 Related Classifications

HY-181994 Related Classifications