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Cat. No.: HY-107681

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Altinicline maleate

(Synonyms: SIB-1508Y)

Altinicline (maleate) is an orally active and selective nAChR agonist. Altinicline (maleate) has the potential to study parkinsonism. Altinicline (maleate) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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CAS No.: 192231-16-6
Formule: C₁₆H₁₈N₂O₄
Masse moléculaire:302.33

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

Altinicline maleate Chemical Structure

CAS No.: 192231-16-6

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

Altinicline (maleate) is an orally active and selective nAChR agonist. Altinicline (maleate) has the potential to study parkinsonism^[1]^[2]. Altinicline (maleate) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Chemical Information

CAS No. 192231-16-6
Masse moléculaire 302.33
Formule C₁₆H₁₈N₂O₄
SMILES

CN1[C@H](C2=CN=CC(C#C)=C2)CCC1.OC(/C=C\C(O)=O)=O
Synonyms

SIB-1508Y
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Cosford ND, et al. (S)-(-)-5-ethynyl-3-(1-methyl-2-pyrrolidinyl)pyridine maleate (SIB-1508Y): a novel anti-parkinsonian agent with selectivity for neuronal nicotinic acetylcholine receptors. J Med Chem. 1996 Aug 16;39(17):3235-7. [Content Brief]

[2]. Schneider JS, et al. Effects of SIB-1508Y, a novel neuronal nicotinic acetylcholine receptor agonist, on motor behavior in parkinsonian monkeys. Mov Disord. 1998 Jul;13(4):637-42. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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