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Cat. No.: HY-186208

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TACC3-IN-3

TACC3-IN-3 is a TACC3 inhibitor. TACC3 is a scaffold protein that is highly expressed in various tumors and regulates microtubule/centrosome stability via phosphorylation by Aurora A. TACC3-IN-3 inhibits the proliferation of triple-negative breast cancer cells. TACC3-IN-3 is applicable to triple-negative breast cancer research.\n

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CAS No.: 3115244-67-9
Formule: C₂₅H₂₇N₅O
Masse moléculaire:413.51

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Please store the product under the recommended conditions in the Certificate of Analysis.

TACC3-IN-3 Chemical Structure

CAS No.: 3115244-67-9

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- In Vitro
Chemical Information
Pureté et documentation
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Activité biologique

Description

Voir tous les produits spécifiques à Isoform Aurora Kinase :

In Vitro

TACC3-IN-3 (Compound 65) inhibits the proliferation of CAL-51 cells after 72 h, with a GI₅₀ value of 0.31 nM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 3115244-67-9
Masse moléculaire 413.51
Formule C₂₅H₂₇N₅O
SMILES

CN1C2=CC=C(C=C2N=C1)C3=CC=NC(NC4=CC(N5C[C@H](O[C@H](C5)C)C)=CC=C4)=C3
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Yang, et al. Tacc inhibitor compound, pharmaceutical composition, and preparation method therefor and use thereof. WO2026026956.

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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TACC3-IN-3

Voir tous les produits spécifiques à Isoform Aurora Kinase

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

TACC3-IN-3 Related Classifications

HY-186208 Related Classifications