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Cat. No.: HY-128613

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Terazosin-md

(Synonyms: TZ-md)

Terazosin-md (compound TZ-md), a derivative of both Alfuzosin (HY-B0192) and Terazosin (HY-B0371), is an orally active α1-adrenergic receptor antagonist. Terazosin-md has the functions of improving mitochondrial metabolism, degrading various pathological protein accumulations and improving the function of vascular endothelial cells. Terazosin-md shows effect in a mouse model with Alzheimer's disease. Terazosin-md can be used for research in Alzheimer's disease and related complications, and diseases associated with protein accumulation and metabolic disorders.

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CAS No.: 2423919-77-9
Formule: C₂₀H₂₆N₄O₄
Masse moléculaire:386.44

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

Terazosin-md Chemical Structure

CAS No.: 2423919-77-9

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
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Classifications
Bioz

Activité biologique

Description

IC₅₀ & Target^[2]

α1-adrenergic receptor

Voir tous les produits spécifiques à Isoform Adrenergic Receptor :

Chemical Information

CAS No. 2423919-77-9
Masse moléculaire 386.44
Formule C₂₀H₂₆N₄O₄
SMILES

O=C(C1OCCC1)N2CCN(CC2)C3=NC(N)=C4C=C(C(OC)=CC4=C3)OC
Synonyms

TZ-md
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Liu Lei, et al. Application of alfuzosin compound in preventing or treating Alzheimer's disease and related diseases. CN111035642A. 2020-04-21.

[2]. Chen X, et al. Terazosin activates Pgk1 and Hsp90 to promote stress resistance. Nat Chem Biol. 2015 Jan;11(1):19-25. [Content Brief]

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Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Chemical Information
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Terazosin-md

Voir tous les produits spécifiques à Isoform Adrenergic Receptor

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

Terazosin-md Related Classifications

HY-128613 Related Classifications