2423919-77-9
Chemical Structure
Terazosin-md
Synonym(s): TZ-md
- CAS No.: 2423919-77-9
- Formula:C20H26N4O4
- Molecular Weight:386.44
IUPAC Name: (4-(1-amino-6,7-dimethoxyisoquinolin-3-yl)piperazin-1-yl)(tetrahydrofuran-2-yl)methanone
InChIKey: ZOUTUYYZIMGRSA-UHFFFAOYSA-N
SMILES: O=C(C1OCCC1)N2CCN(CC2)C3=NC(N)=C4C=C(C(OC)=CC4=C3)OC
Biological Activity: Terazosin-md (compound TZ-md), a derivative of both Alfuzosin (HY-B0192) and Terazosin (HY-B0371), is an orally active α1-adrenergic receptor antagonist. Terazosin-md has the functions of improving mitochondrial metabolism, degrading various pathological protein accumulations and improving the function of vascular endothelial cells. Terazosin-md shows effect in a mouse model with Alzheimer's disease. Terazosin-md can be used for research in Alzheimer's disease and related complications, and diseases associated with protein accumulation and metabolic disorders[1][2].
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Terazosin-md | Terazosin-md (compound TZ-md), a derivative of both Alfuzosin (HY-B0192) and Terazosin (HY-B0371), is an orally active α1-adrenergic receptor antagonist. Terazosin-md has the functions of improving mitochondrial metabolism, degrading various pathological protein accumulations and improving the function of vascular endothelial cells. Terazosin-md shows effect in a mouse model with Alzheimer's disease. Terazosin-md can be used for research in Alzheimer's disease and related complications, and diseases associated with protein accumulation and metabolic disorders. | |||||||||||||||||||||
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Keywords
