1-Acetyl-DHAP
1-Acetyl-DHA (Compound 7) is a substrate of the phosphotriesterase homology protein (PHP) and can be hydrolyzed by PHP with a kcat/km value of 100 M-1s-1. The level of 1-Acetyl-DHA is regulated by mTORC1 and is negatively correlated with the nuclear acetate level. 1-Acetyl-DHA plays an important role in cellular metabolism and the regulation of histone acetylation.
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- CAS. Nr.: 2267338-53-2
- Formel: C5H9O7P
- Molecular Weight:212.09
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Biologische Aktivität
Chemical Information
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CAS. Nr. 2267338-53-2
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Molecular Weight 212.09
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Formel C5H9O7P
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SMILES
O=C(C)OCC(COP(O)(O)=O)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Nemmara VV, et al. Substrate Profile of the Phosphotriesterase Homology Protein from Escherichia coli. Biochemistry. 2018 Oct 30;57(43):6219-6227. [Content Brief]
[2]. Zhang JJ, et al. Nuclear dihydroxyacetone phosphate signals nutrient sufficiency and cell cycle phase to global histone acetylation. Nat Metab. 2021 Jun;3(6):859-875. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
1-Acetyl-DHAP Related Classifications
HY-171229 Related Classifications
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