BChE-IN-39
BChE-IN-39 (Compound 7c) is a selective inhibitor for butyrylcholinesterase (BChE) with an IC50 of 0.08 μM (IC50=3.98 μM for AChE). BChE-IN-39 downregulates the GSK-3β expression, inhibits the hyperphosphorylation of tau protein.
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- Formel: C29H23ClFN3O3
- Molecular Weight:515.96
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
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BChE 0.08 μM (IC50) |
AChE 3.98 μM (IC50) |
Chemical Information
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Molecular Weight 515.96
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Formel C29H23ClFN3O3
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SMILES
FC1=CC(C[N+]2=CC=CC(CNC(C3=CC=C(CN(C(C4=C5C=CC=C4)=O)C5=O)C=C3)=O)=C2)=CC=C1.[Cl-]
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)