BLT2 antagonist-1
BLT2 antagonist-1 (compound 15b) is a selective BLT2 antagonist that inhibits the chemotaxis of CHO-BLT2 cells with an IC50 of 224 nM. BLT2 antagonist-1 does not inhibits the chemotaxis of CHO-BLT1 cells. BLT2 antagonist-1 also inhibits the binding of LTB4 and BLT2 with a Ki value of 132 nM. BLT2 antagonist-1 can be used for the research of the inflammatory airway diseases such as asthma and chronic obstructive pulmonary disease.
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- CAS. Nr.: 2069220-61-5
- Formel: C26H26FNO4
- Molecular Weight:435.49
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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BLT2 224 nM (IC50) |
Chemical Information
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CAS. Nr. 2069220-61-5
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Molecular Weight 435.49
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Formel C26H26FNO4
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SMILES
O=C(CCCC)N(C1=CC=CC(F)=C1)CC2=CC=C(C3=CC=C(OCC(O)=O)C=C3)C=C2
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
BLT2 antagonist-1 Related Classifications
HY-155300 Related Classifications
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