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Art. -Nr.: HY-15592S4

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Cabotegravir-d₆

(Synonyms: GSK-1265744-d₆; S/GSK1265744-d₆)

Cabotegravir-d₆ (GSK-1265744-d₆) is the deuterium labeled Cabotegravir (HY-15592). Cabotegravir (GSK-1265744) is a orally active and long-acting HIV integrase strand transfer inhibitor and organic anion transporter 1/3 (OAT1/OAT3) inhibitor with IC₅₀ values of 2.5 nM, 0.41 μM and 0.81 μM for HIV_ADA, OAT3 and OAT1, respectively. Cabotegravir is primarily metabolized by uridine diphosphate glucuronosyltransferase (UGT) 1A1, with low potential to interact with other antiretroviral agents (ARVs). Cabotegravir can be used to research AIDS.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

Formel: C₁₉H₁₁D₆F₂N₃O₅
Molecular Weight:411.39

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Cabotegravir-d₆ Chemical Structure

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Biologische Aktivität
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Chemical Information
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Bioz

Biologische Aktivität

Beschreibung

Alle HIV Isoform-spezifische Produkte anzeigen :

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Anwendung

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

Unlabeled Cas 1051375-10-0
Molecular Weight 411.39
Formel C₁₉H₁₁D₆F₂N₃O₅
SMILES

O=C(C1=CN(C2=C(O)C1=O)C[C@](OC([2H])([2H])[C@]3([2H])C([2H])([2H])[2H])([H])N3C2=O)NCC4=CC=C(F)C=C4F
Synonyms

GSK-1265744-d₆; S/GSK1265744-d₆
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.