DHODH-IN-3
DHODH-IN-3 (compound 3) is a potent inhibitor of Human Dihydroorotate Dehydrogenases (HsDHODH) with an IC50 value of 261 nM. DHODH-IN-3 binds to the the ubiquinone binding cavities in DHODH with a Kiapp of 32 nM. DHODH-IN-3 has the potential for malaria treatment.
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- CAS. Nr.: 1148126-04-8
- Formel: C17H13ClN2O2
- Molecular Weight:312.75
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
IC50: 261 nM (HsDHODH)[1]
DHODH-IN-3 (compound 3) show good inhibitory effects on HsDHODH with IC50 value of 261 nM. It binds to HsDHODH with a Kiapp value of 32 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 1148126-04-8
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Molecular Weight 312.75
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Formel C17H13ClN2O2
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SMILES
C/C(O)=C(C#N)/C(NC1=CC=C(C2=CC=CC=C2)C=C1Cl)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
DHODH-IN-3 Related Classifications
HY-135618 Related Classifications
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