iNOs-IN-5
iNOs-IN-5 (Compound BN-4) is an inhibitor for iNOS with an IC50 of 0.1707 μM, and reduces NO levels in LPS (HT-D1056)-induced RAW264.7 cells. iNOs-IN-5 reduces the hypoxic injury stimulated ROS and lactate dehydrogenase expression, and exhibits anti-necrosis and anti-apoptosis efficacy. iNOs-IN-5 exhibits anti-cerebral ischemia and neuroprotective activities in SD rat models. iNOs-IN-5 is blood-brain barrier penetrable.
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- CAS. Nr.: 3067565-40-3
- Formel: C22H27N3O2
- Molecular Weight:365.47
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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iNOS 0.1707 μM (IC50) |
Chemical Information
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CAS. Nr. 3067565-40-3
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Molecular Weight 365.47
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Formel C22H27N3O2
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SMILES
O=C(OC1CCCC)C2=C1C=CC(NCC3=CC(CNC(C)=N)=CC=C3)=C2
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
iNOs-IN-5 Related Classifications
HY-168096 Related Classifications
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