RdRP-IN-8
RdRP-IN-8 (compound 45) is an anti-influenza virus compound. RdRP-IN-8 inhibits viral RNA-dependent RNA polymerase (RdRP) activity by disrupting heterodimerization of PA and PB1 subunits (EC50=0.13 μM).
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C23H21N3O6S
- Molecular Weight:467.49
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
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Biologische Aktivität
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RNA Polymerase |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | CC50 |
>40 μM
Compound: 45
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Cytotoxicity against human A549 cells
Cytotoxicity against human A549 cells
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[PMID: 39153334] |
| HEK-293T | CC50 |
>50 μM
Compound: 45
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Cytotoxicity against HEK293T cells incubated for 48 hrs by MTT assay
Cytotoxicity against HEK293T cells incubated for 48 hrs by MTT assay
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[PMID: 39153334] |
| MDCK | CC50 |
224 μM
Compound: 45
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Cytotoxicity against MDCK cells incubated for 48 hrs by MTT assay
Cytotoxicity against MDCK cells incubated for 48 hrs by MTT assay
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[PMID: 39153334] |
Chemical Information
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Molecular Weight 467.49
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Formel C23H21N3O6S
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SMILES
O=C(C1=C(O)C=C([N+]([O-])=O)C=C1)NC(S2)=C(C(NC3=CC=CC=C3O)=O)C4=C2CCCCC4
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
RdRP-IN-8 Related Classifications
HY-162793 Related Classifications
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