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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3002 Results for "
affinity
" in MedChemExpress (MCE) Product Catalog:
Products (3002)
3002 Results for "affinity" in MCE Product Catalog:
379
379 Publications Verification
Synonyms: DMSO, meets analytical specification of Ch.P.
MCE provides Dimethyl sulfoxide that complies with the inspection standards (Ch.P) of Part 4 of the Chinese Pharmacopoeia (2020 Edition). Amicrobic, low endotoxin, can be used in various biochemical experiments such as drug dissolution.
314
314 Cited Publications
Forschungsgebiete:
Stattic is a potent STAT3 inhibitor and inhibits STAT3 phosphorylation (at Y705 and S727) . Stattic inhibits the binding of a high affinity phosphopeptide for the SH2 domain of STAT3 . Stattic ameliorates the renal dysfunction in Alport syndrome (AS) mice .
71
71 Cited Publications
Art. -Nr.: HY-19370
CAS. Nr.: 945714-67-0
Target:
Forschungsgebiete:
FPS-ZM1 is a high-affinity and BBB-permeable RAGE inhibitor with a Ki of 25 nM.
70
70 Cited Publications
Synonyms: 17-AAG; NSC 330507; CP 127374
Tanespimycin (17-AAG) is a potent HSP90 inhibitor with an IC50 of 5 nM, having a 100-fold higher binding affinity for tumour cell derived HSP90 than normal cell derived HSP90 . Tanespimycin depletes cellular STK38/NDR1 and reduces STK38 kinase activity. Tanespimycin also downregulates the stk38 gene expression .
66
66 Cited Publications
Art. -Nr.: HY-P9907
CAS. Nr.: 180288-69-1
Synonyms: Anti-Human HER2, Humanized Antibody
Forschungsgebiete:
62
62 Cited Publications
Art. -Nr.: HY-P9906
CAS. Nr.: 216974-75-3
Synonyms: Anti-Human VEGF, Humanized Antibody
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62 Cited Publications
Art. -Nr.: HY-P9906A
CAS. Nr.: 216974-75-3
57
Target:
Forschungsgebiete:
Tariquidar (XR9576) is a potent and specific inhibitor of P-glycoprotein (P-gp) with the high affinity (Kd=5.1 nM) .
54
54 Cited Publications
Target:
Forschungsgebiete:
GSK484 hydrochloride is a selective and reversible peptidylarginine deiminase 4 (PAD4) inhibitor. GSK484 hydrochloride demonstrates high affinity binding to PAD4 with IC50s of 50 nM in the absence of Calcium. In the presence of 2 mM Calcium, notably lower potency (250 nM) is observed.
53
Low endotoxin, can be used in various biochemical experiments such as drug dissolution.
52
52 Cited Publications
Synonyms: MC 903; Calcipotriene
Target:
Forschungsgebiete:
Calcipotriol is a synthetic VitD3 analogue with a high affinity for the vitamin D receptor.
52
52 Cited Publications
Target:
Forschungsgebiete:
Calcipotriol monohydrate is a synthetic VitD3 analogue with a high affinity for the vitamin D receptor.
52
Forschungsgebiete:
Doramapimod (BIRB 796) is an orally active, highly potent p38 MAPK inhibitor, which has an IC50 for p38α=38 nM, for p38β=65 nM, for p38γ=200 nM, and for p38δ=520 nM. Doramapimod has picomolar affinity for p38 kinase (Kd=0.1 nM). Doramapimod also inhibits B-Raf with an IC50 of 83 nM .
50
Target:
Forschungsgebiete:
Pioglitazone (U 72107) is an orally active and selective PPARγ (peroxisome proliferator-activated receptor) agonist with high affinity binding to the PPARγ ligand-binding domain with EC50 of 0.93 and 0.99 μM for human and mouse PPARγ, respectively. Pioglitazone can be used in diabetes research .
50
Category:
Alkaloids Neurological Disease Other Alkaloids Endogenous metabolite Disease Research Fields Endocrinology
Target:
50
Category:
Cardiovascular Disease Alkaloids Neurological Disease Other Alkaloids Endogenous metabolite Disease Research Fields
Target:
42
42 Cited Publications
Target:
Forschungsgebiete:
G15 is a high affinity and selective G-protein-coupled estrogen receptor (GPER/GPR30) antagonist with a Ki of 20 nM .
42
42 Cited Publications
Synonyms: 2'-3'-cyclic GMP-AMP
Target:
42
42 Cited Publications
Synonyms: 2'-3'-cyclic GMP-AMP sodium
Target:
42
42 Cited Publications
Art. -Nr.: HY-D0989
CAS. Nr.: 145037-81-6
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
