Vitamin D3-d7
Based on 1 Customer Validation
Vitamin D3-d7 is the deuterium labeled Vitamin D3. Vitamin D3 (Cholecalciferol) is a naturally occuring form of vitamin D. Vitamin D3 induces cell differentiation and prevents proliferation of cancer cells.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit: 95.0%
- CAS. Nr.: 1627523-19-6
- Formel: C27H37D7O
- Molecular Weight:391.68
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Speicherung:
-80°C, protect from light, stored under nitrogen
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
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Biologische Aktivität
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS. Nr. 1627523-19-6
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Unlabeled Cas 67-97-0
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Appearance Solid
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Molecular Weight 391.68
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Formel C27H37D7O
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Color White to off-white
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SMILES
C=C1CC[C@@H](C/C1=C/C=C2[C@@]([H])([C@@]3(CCC/2)C)CC[C@]3([H])[C@@H](CCCC([2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])C)O
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Versand
Shipping with dry ice.
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Speicherung
-80°C, protect from light, stored under nitrogen
Lösungsmittel & Löslichkeit
DMSO : 100 mg/mL (255.31 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (276 KB)
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SDS (584 KB)
- English - EN (584 KB)
- Français - FR (584 KB)
- Deutsch - DE (584 KB)
- Norwegian - NO (584 KB)
- Español - ES (584 KB)
- Swedish - SV (584 KB)
- Italian - IT (584 KB)
- Korean - KR (584 KB)
- Portuguese - PT (584 KB)
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Handling Instructions (2659 KB)
Verweise
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Nazik Al-Hashimi, et al. Cholecalciferol
[3]. Laura Bergadà, et al. Role of local bioactivation of vitamin D by CYP27A1 and CYP2R1 in the control of cell growth in normal endometrium and endometrial carcinoma. Lab Invest. 2014 Jun;94(6):608-22 [Content Brief]
[4]. Hiroki Yoshioka, et al. Vitamin D3-induced hypercalcemia increases carbon tetrachloride-induced hepatotoxicity through elevated oxidative stress in mice. PLoS One. 2017 Apr 27;12(4):e0176524. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.5531 mL | 12.7655 mL | 25.5310 mL | 63.8276 mL |
| 5 mM | 0.5106 mL | 2.5531 mL | 5.1062 mL | 12.7655 mL | |
| 10 mM | 0.2553 mL | 1.2766 mL | 2.5531 mL | 6.3828 mL | |
| 15 mM | 0.1702 mL | 0.8510 mL | 1.7021 mL | 4.2552 mL | |
| 20 mM | 0.1277 mL | 0.6383 mL | 1.2766 mL | 3.1914 mL | |
| 25 mM | 0.1021 mL | 0.5106 mL | 1.0212 mL | 2.5531 mL | |
| 30 mM | 0.0851 mL | 0.4255 mL | 0.8510 mL | 2.1276 mL | |
| 40 mM | 0.0638 mL | 0.3191 mL | 0.6383 mL | 1.5957 mL | |
| 50 mM | 0.0511 mL | 0.2553 mL | 0.5106 mL | 1.2766 mL | |
| 60 mM | 0.0426 mL | 0.2128 mL | 0.4255 mL | 1.0638 mL | |
| 80 mM | 0.0319 mL | 0.1596 mL | 0.3191 mL | 0.7978 mL | |
| 100 mM | 0.0255 mL | 0.1277 mL | 0.2553 mL | 0.6383 mL |
Vitamin D3-d7 Related Classifications
HY-15398S Related Classifications
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