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Cat. No.: HY-N15612

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5-Hydroxy-7-methoxycoumarin

5-Hydroxy-7-methoxycoumarin is a coumarin compound present in the whole plant of Euphorbia kansuensis, with an IC₅₀ > 40 μM against five human cancer cell lines.

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CAS No.: 23053-61-4
Formule: C₁₀H₈O₄
Masse moléculaire:192.17

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

5-Hydroxy-7-methoxycoumarin Chemical Structure

CAS No.: 23053-61-4

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

5-Hydroxy-7-methoxycoumarin is a coumarin compound present in the whole plant of Euphorbia kansuensis, with an IC₅₀ > 40 μM against five human cancer cell lines^[1].

In Vitro

5-Hydroxy-7-methoxycoumarin (0.0625-40 μM; 48 h) exhibits no significant activity against human cancer cell lines in vitro^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cytotoxicity Assay^[1]

Cell Line:

HL-60 (human myeloid leukemia), SMMC-7721 (hepatocellular carcinoma), A-549 (human lung cancer), MCF-7 (human breast carcinoma), SW-480 (colon cancer)
Concentration:

0.0625, 0.32, 1.6, 8, 40 μM
Incubation Time:

48 h
Result:

Showed no cytotoxic activity against all tested human cancer cell lines, with an IC₅₀ value > 40 μM.

Chemical Information

CAS No. 23053-61-4
Masse moléculaire 192.17
Formule C₁₀H₈O₄
SMILES

O=C1OC=2C=C(OC)C=C(O)C2C=C1
Structure Classification
- Phenylpropanoids
- Coumarins
Initial Source
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Zhang BY, et al. Chemical constituents of Euphorbia tangutica. Nat Prod Res. 2012;26(24):2309-2315. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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