Dicentrine hydrochloride
Dicentrine hydrochloride is a drug with anti-inflammatory and anti-cancer activity. Dicentrine hydrochloride exerts its effects by enhancing TNF-α-induced apoptosis in A549 lung adenocarcinoma cells. Dicentrine hydrochloride increases caspase-8, -9, -3 and poly(ADP-ribose) polymerase (PARP) activities. Dicentrine hydrochloride inhibits TNF-α-induced invasion and migration of A549 cells. Dicentrine hydrochloride significantly inhibited the TNF-α-activated TAK1, p38, JNK and Akt signaling pathways, and reduced the transcriptional activities of NF-κB and AP-1.
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- CAS No.: 5742-03-0
- Formule: C20H22ClNO4
- Masse moléculaire:375.85
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
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Activité biologique
Chemical Information
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CAS No. 5742-03-0
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Masse moléculaire 375.85
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Formule C20H22ClNO4
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SMILES
CN1[C@]2([H])C3=C(CC1)C=C(OCO4)C4=C3C5=CC(OC)=C(OC)C=C5C2.Cl
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Structure Classification
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Initial Source
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Dicentrine hydrochloride Related Classifications
HY-N6969A Related Classifications
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