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Cat. No.: HY-182102

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NLRP3-IN-88

NLRP3-IN-88 (Compound 1) is an NLRP3 inhibitor. NLRP3-IN-88 inhibits IL-1β. NLRP3-IN-88 can be used in research on intestinal diseases and inflammatory diseases.

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CAS No.: 2557349-73-0
Formule: C₁₈H₂₁F₃N₄O
Masse moléculaire:366.38

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

NLRP3-IN-88 Chemical Structure

CAS No.: 2557349-73-0

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
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Activité biologique

Description

NLRP3-IN-88 (Compound 1) is an NLRP3 inhibitor. NLRP3-IN-88 inhibits IL-1β. NLRP3-IN-88 can be used in research on intestinal diseases and inflammatory diseases.

IC₅₀ & Target^[1]

IL-1β

NLRP3

Voir tous les produits spécifiques à Isoform NOD-like Receptor (NLR) :

Voir tous les produits spécifiques à Isoform Interleukin Related :

In Vitro

NLRP3-IN-88 (10 doses starting from 5 μΜ; 3 h) inhibits IL-1β in THP-1 cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2557349-73-0
Masse moléculaire 366.38
Formule C₁₈H₂₁F₃N₄O
SMILES

OC1=C(C2=C(C=C(N=N2)N[C@H]3CN(CCC3)C)C)C=CC(C(F)(F)F)=C1
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Hongjian Zhang, et al. Gut-directed inhibitors of nlrp3 activity and therapeutic uses thereof. WO2026030710A1. WIPO (PCT). 2025-08-01.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
Références

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NLRP3-IN-88

Voir tous les produits spécifiques à Isoform NOD-like Receptor (NLR)

Voir tous les produits spécifiques à Isoform Interleukin Related

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

NLRP3-IN-88 Related Classifications

HY-182102 Related Classifications