ROCK-IN-13
ROCK-IN-13 is a ROCK2 inhibitor with an IC50 of 8 nM against human ROCK2. ROCK-IN-13 has the potential for use in the research of diseases such as multiple sclerosis, glaucoma, and cardiovascular diseases.
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- CAS No.: 1219727-16-8
- Formule: C20H22N4O
- Masse moléculaire:334.41
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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ROCK2 8 nM (IC50) |
ROCK-IN-13 (Compound D3) (4 h) potently inhibits recombinant human ROCK2, with an IC50 value of 8 nM[1].
ROCK-IN-13 (70 min) weakly inhibits recombinant human PKA, with an experimental IC50 of 3381 nM, and shows 422-fold higher selectivity for ROCK2 than for PKA[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1219727-16-8
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Masse moléculaire 334.41
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Formule C20H22N4O
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SMILES
O=C(N(C(C)C)CC1=CC=CC=C1)NC2=CC=C(C=C2)C3=CNN=C3
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ROCK-IN-13 Related Classifications
HY-116233 Related Classifications
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