VEGFR-2-IN-55
VEGFR-2-IN-55 (Compound 30) is a potent VEGFR-2 kinase inhibitor with an IC50 value of 1.24 nM . VEGFR-2-IN-55 has antitumor activity.
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- Formule: C28H21FN4OS
- Masse moléculaire:480.56
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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VEGFR-2 1.24 nM (IC50) |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| BaF3 | GI50 |
>10000 nM
Compound: 30
|
Growth inhibition of mouse BaF3 incubated for 72 hrs by CCK-8 assay
Growth inhibition of mouse BaF3 incubated for 72 hrs by CCK-8 assay
|
[PMID: 39353237] |
| BaF3 | GI50 |
1.42 nM
Compound: 30
|
Growth inhibition of mouse BaF3 cells harboring TEL-VEGFR2 incubated for 72 hrs by CCK-8 assay
Growth inhibition of mouse BaF3 cells harboring TEL-VEGFR2 incubated for 72 hrs by CCK-8 assay
|
[PMID: 39353237] |
Chemical Information
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Masse moléculaire 480.56
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Formule C28H21FN4OS
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SMILES
O=C(NC1=CC=CC(SC2=CC3=C(C=C2)C(/C=C/C4=NC=CC=C4)=NN3)=C1)CC5=CC=CC=C5F
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)