6-Bromooxindole
Based on 1 Customer Validation
6-Bromo-2-oxindole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit: 98.12%
- CAS. Nr.: 99365-40-9
- Formel: C8H6BrNO
- Molecular Weight:212.04
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Speicherung:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biologische Aktivität
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MDA-MB-231 | IC50 |
74 μM
Compound: 26
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Anticancer activity against human MDA-MB-231 cells assessed as cell growth incubated for 24 hrs by MTT assay
Anticancer activity against human MDA-MB-231 cells assessed as cell growth incubated for 24 hrs by MTT assay
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[PMID: 36853972] |
6-Bromo-2-oxindole is a secondary metabolite that has been isolated from the sea squirt (D. skoogi). It is cytotoxic to MDA-MB-231 breast cancer cells with an IC50 value of 74.41 μM. 6-Bromo-2-oxindole has been used in the synthesis of 1,3-disstituted 2-oxindoles and indolin-2-one p38α inhibitors, which have anti-inflammatory activity.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 99365-40-9
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Appearance Solid
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Molecular Weight 212.04
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Formel C8H6BrNO
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Color White to light brown
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SMILES
O=C1NC2=C(C=CC(Br)=C2)C1
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Synonyms
6-Bromo-2-oxindole
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Lösungsmittel & Löslichkeit
DMSO : 100 mg/mL (471.61 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (242 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.7161 mL | 23.5805 mL | 47.1609 mL | 117.9023 mL |
| 5 mM | 0.9432 mL | 4.7161 mL | 9.4322 mL | 23.5805 mL | |
| 10 mM | 0.4716 mL | 2.3580 mL | 4.7161 mL | 11.7902 mL | |
| 15 mM | 0.3144 mL | 1.5720 mL | 3.1441 mL | 7.8602 mL | |
| 20 mM | 0.2358 mL | 1.1790 mL | 2.3580 mL | 5.8951 mL | |
| 25 mM | 0.1886 mL | 0.9432 mL | 1.8864 mL | 4.7161 mL | |
| 30 mM | 0.1572 mL | 0.7860 mL | 1.5720 mL | 3.9301 mL | |
| 40 mM | 0.1179 mL | 0.5895 mL | 1.1790 mL | 2.9476 mL | |
| 50 mM | 0.0943 mL | 0.4716 mL | 0.9432 mL | 2.3580 mL | |
| 60 mM | 0.0786 mL | 0.3930 mL | 0.7860 mL | 1.9650 mL | |
| 80 mM | 0.0590 mL | 0.2948 mL | 0.5895 mL | 1.4738 mL | |
| 100 mM | 0.0472 mL | 0.2358 mL | 0.4716 mL | 1.1790 mL |