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Art. -Nr.: HY-N12817

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Anti-inflammatory agent 80

Anti-inflammatory agent 80 (Compound 2/2f) is an anti-inflammatory agent and has anti-tumor activity. Anti-inflammatory agent 80 can be isolated fromCynanchum limprichtiiSchltr.

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CAS. Nr.: 2128277-55-2
Formel: C₄₀H₆₀O₁₃
Molecular Weight:748.90

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Anti-inflammatory agent 80 Chemical Structure

CAS. Nr.: 2128277-55-2

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Biologische Aktivität
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- In Vitro
Chemical Information
Reinheit & Dokumentation
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Calculators
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Biologische Aktivität

Beschreibung

Anti-inflammatory agent 80 (Compound 2/2f) is an anti-inflammatory agent and has anti-tumor activity. Anti-inflammatory agent 80 can be isolated fromCynanchum limprichtiiSchltr^[1]^[2].

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In Vitro

Anti-inflammatory agent 80 (Compound 2) is cytotoxic to the human cancer cell line HL60^[1].
Anti-inflammatory agent 80 (Compound 2f) (100 μM; 1 h) significantly inhibits LPS-induced iNOS protein expression in RAW264.7 cells ^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Western Blot Analysis^[2]

Cell Line:

RAW264.7 cells
Concentration:

100 μM
Incubation Time:

1 h
Result:

Significantly inhibited LPS-induced iNOS protein expression.

Chemical Information

CAS. Nr. 2128277-55-2
Molecular Weight 748.90
Formel C₄₀H₆₀O₁₃
SMILES

C[C@]12[C@]([C@](CO2)([H])O3)([H])[C@]4(CO1)C3=C(CC=C(C5)[C@@]6(CC[C@@H]5O[C@H](O[C@@H]7C)C[C@H]([C@@H]7O[C@H](O[C@@H]8C)C[C@@H]([C@@H]8O[C@H](O[C@H]9C)C[C@H]([C@H]9O)OC)O)O)C)[C@]6([H])CC4
Structure Classification
- Steroids
- Cardiacglycosides
Initial Source
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Liu JC, et al. Two new 14, 15-secopregnane-type steroidal glycosides from the roots of Cynanchum limprichtii. Nat Prod Res. 2018 Feb;32(3):261-267. [Content Brief]

[2]. Lai C, et al. Hirundigenin type C 21 steroidal glycosides from Cynanchum stauntonii and their anti-inflammatory activity[J]. RSC advances, 2016, 6(64): 59257-59268.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Anti-inflammatory agent 80

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Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

Anti-inflammatory agent 80 Related Classifications

HY-N12817 Related Classifications