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Cat. No.: HY-153761

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ASK1-IN-4

ASK1-IN-4 (Compound 17) is an ASK1 inhibitor (IC₅₀=0.2 μM). ASK1-IN-4 interacts with ATP-binding site of ASK1.

For research use only. We do not sell to patients.

CAS No.: 1427538-26-8
Formula: C₁₈H₁₄BrNO₄S₂
Molecular Weight:452.34

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

ASK1-IN-4 Chemical Structure

CAS No.: 1427538-26-8

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

ASK1-IN-4 (Compound 17) is an ASK1 inhibitor (IC₅₀=0.2 μM). ASK1-IN-4 interacts with ATP-binding site of ASK1^[1].

IC₅₀ & Target

ASK1

.2 μM (IC₅₀)

All MAP3K Isoforms :

Chemical Information

CAS No. 1427538-26-8
Molecular Weight 452.34
Formula C₁₈H₁₄BrNO₄S₂
SMILES

BrC(C=C1)=CC=C1C2=CC=C(O2)/C=C3C(N(C(S/3)=S)CCCC(O)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Starosyla SA,et al. ASK1 pharmacophore model derived from diverse classes of inhibitors. Bioorg Med Chem Lett. 2014 Sep 15;24(18):4418-4423. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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ASK1-IN-4

All MAP3K Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

ASK1-IN-4 Related Classifications

HY-153761 Related Classifications