Aldh1a2 - aldehyde dehydrogenase 1 family, member A2 Gene

Also Known as Raldh-2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 116676

Summary

Enables retinal binding activity and retinal dehydrogenase activity. Involved in several processes, including gland development; response to vitamin A; and retinoic acid biosynthetic process. Located in cytosol and perinuclear region of cytoplasm. Orthologous to human ALDH1A2 (aldehyde dehydrogenase 1 family member A2). [provided by Alliance of Genome Resources, Apr 2022]

Aldh1a2 Products (1)

mRNA Protein Name
NM_053896.2 NP_446348.2 retinal dehydrogenase 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables retinal binding IDA
IDA: Inferred from direct assay
8663198 RGD
enables retinal dehydrogenase activity IDA
IDA: Inferred from direct assay
12547725 RGD
Biological Process GO Annotation Evidence References Source
involved in kidney development IEP
IEP: Inferred from expression pattern
15567713 RGD
involved in liver development IEP
IEP: Inferred from expression pattern
14729401 RGD
involved in midgut development IEP
IEP: Inferred from expression pattern
15964596 RGD
involved in pituitary gland development IEP
IEP: Inferred from expression pattern
17180597 RGD
involved in response to estradiol IEP
IEP: Inferred from expression pattern
15205379 RGD
involved in response to vitamin A IEP
IEP: Inferred from expression pattern
11169459 RGD
involved in retinoic acid biosynthetic process IEP
IEP: Inferred from expression pattern
15950969 RGD
involved in retinoic acid biosynthetic process IMP
IMP: Inferred from mutant phenotype
21138835 RGD
involved in retinoic acid metabolic process IDA
IDA: Inferred from direct assay
12547725 RGD
Cellular Component GO Annotation Evidence References Source
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
21138835 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

retinal dehydrogenase 2

  • RALDH 2

  • RalDH(II)

  • aldehyde dehydrogenase 1A2

  • aldehyde dehydrogenase family 1 member A2

  • aldehyde dehydrogenase family 1, subfamily A2

  • ralDH2

  • retinal dehydrogenase, type II

  • retinaldehyde-specific dehydrogenase type 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (15)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-W011094 Win 18446 Inhibitor 98.94% Unkown
HY-125085 ALDH3A1-IN-3 Inhibitor 99.43% Unkown
HY-122912 ALDH1A inhibitor 673A 99.15% Unkown
HY-135841 CM010 Inhibitor 99.70% Unkown
HY-139031 ALDH1A2-IN-1 Inhibitor 98.05% Unkown
HY-157567 FSI-TN42 Inhibitor 98.05% Unkown
HY-128299 ALDH3A1-IN-4 Inhibitor 99.91% Unkown
HY-139032 CM121 Inhibitor 99.95% Unkown
HY-158026 ALDH1A1-IN-5 Inhibitor / Unkown
HY-N11451 Lacto-N-fucopentaose III Activator 96.54% Unkown
HY-RS00561 Aldh1a1 Mouse Pre-designed siRNA Set A / Unkown
HY-RS00563 ALDH1A2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS00567 ALDH1L2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17028 Aldh1a2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23472 Aldh1a2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Aldh1a2 NCBI NCBI:8854