2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Dipivefrin hydrochloride

Dipivefrin hydrochloride  (Synonyms: Dipivefrine hydrochloride)

Cat. No.: HY-B1323 Purity: 99.82%
COA Handling Instructions

Dipivefrin hydrochloride (Dipivefrine hydrochloride) is an antiglaucoma proagent that is hydrolyzed to the active compound, epinephrine, by esterases in the cornea.

For research use only. We do not sell to patients.

Dipivefrin hydrochloride Chemical Structure

Dipivefrin hydrochloride Chemical Structure

CAS No. : 64019-93-8

Size Price Stock Quantity
Solution
10 mM * 1 mL in DMSO USD 55 In-stock
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
 USD 55 In-stock
Solid
5 mg USD 32 In-stock
10 mg USD 50 In-stock
25 mg USD 100 In-stock
50 mg USD 160 In-stock
100 mg USD 250 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

Other Forms of Dipivefrin hydrochloride:

Dipivefrin hydrochloride Related Antibodies

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Description

Dipivefrin hydrochloride (Dipivefrine hydrochloride) is an antiglaucoma proagent that is hydrolyzed to the active compound, epinephrine, by esterases in the cornea[1][2].

In Vivo

Dipivefrin hydrochloride (0.3-10 μg/kg; i.p.;) induces enhancement of memory involves central beta- but not alpha-adrenergic mechanisms[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male 60-day-old CFW mice (23-28 g)[3]
Dosage: 0.3 μg/kg, 1.0 μg/kg, 3.0 μg/kg, 10 μg/kg
Administration: Intraperitoneal injection; post-training
Result: Significantly enhanced retention of both inhibitory avoidance and Y-maze discrimination tasks in a dose-dependent manner.
Molecular Weight

387.90

Appearance

Solid

Formula

C19H30ClNO5
CAS No.
SMILES

CNCC(C1=CC=C(OC(C(C)(C)C)=O)C(OC(C(C)(C)C)=O)=C1)O.[H]Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, stored under nitrogen, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)
Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (644.50 mM; Need ultrasonic)

H2O : ≥ 100 mg/mL (257.80 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5780 mL 12.8899 mL 25.7798 mL
5 mM 0.5156 mL 2.5780 mL 5.1560 mL
10 mM 0.2578 mL 1.2890 mL 2.5780 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (5.36 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (5.36 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (5.36 mM); Clear solution

*All of the co-solvents are available by MCE.
Purity & Documentation
References
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Dipivefrin hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Dipivefrin64019-93-8DipivefrineEndogenous MetaboliteantiglaucomaepinephrineprodrugInhibitorinhibitorinhibit

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