Cic - capicua transcriptional repressor Gene

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Predicted to be involved in several processes, including learning or memory; regulation of transcription, DNA-templated; and social behavior. Predicted to act upstream of or within lung alveolus development and negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Predicted to be part of protein-containing complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in autosomal dominant mental retardation 45. Orthologous to human CIC (capicua transcriptional repressor). [provided by Alliance of Genome Resources, Apr 2022]