Antibacterial agent 124
Antibacterial agent 124 (Compound 3) is a potent bacterial prolyl-tRNA synthetase (ProRS) inhibitor with an IC50 of 0.18 μM against Staphylococcus aureus ProRS (SaProRS).
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- No. CAS: 2304448-00-6
- Fòrmula: C16H17ClFN3O2
- Peso molecular:337.78
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | CC50 |
0.076 μM
Compound: 3
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Cytotoxicity against human HepG2 cells
Cytotoxicity against human HepG2 cells
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[PMID: 36394909] |
Antibacterial agent 124 (Compound 3) shows antibacterial activity with MICs of 1, 1, 4, 1, 1, 2 and 4 μg/mL against E. coli (ATCC25922), S. flexneri (CMCC51572), S. typhi (CMCC50094), MRSA252, MRSA R3708, S. aureus ATCC29213, S. aureus ATCC25923, respectively. And the CC50 to HepG2 is 4.32 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 2304448-00-6
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Peso molecular 337.78
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Fòrmula C16H17ClFN3O2
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SMILES
O=C(CN1C=NC2=CC(Cl)=C(C=C2C1=O)F)C[C@@H]3CCCCN3
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Antibacterial agent 124 Related Classifications
HY-151880 Related Classifications
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