Coixenolide
Based on 1 Customer Validation
Coixenolide can be isolated from coix seeds, and exhibits anti-inflammatory, anti-tumor and pain-reducing activities. Coixenolide stimulates the lung, heart, striated and smooth muscles at low doses, while inhibits at high doses. Coixenolide dilates pulmonary veins and improves pulmonary blood circulation. Coixenolide can also be used as nutraceuticals and functional foods. Coixenolide enhances the prodcutionof mycelia biomass and polysaccharides when added to the media of submerged culture of G. lucidum. Coixenolide affects the synthesis level of phosphoglucose isomerase and α-phosphoglucomutase.
For research use only. We do not sell to patients.
- Purity: 99.93%
- CAS No.: 29066-43-1
- Formula: C38H70O4
- Molecular Weight:590.96
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
Coixenolide (0-1 %, 7 d) enhances the mycelial growth and polysaccharide production[2].
Coixenolide (0-0.25 %, 1-9 d) results in a quicker decrease in the glucose concentration of culture compared to the control[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 29066-43-1
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Appearance Oil
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Molecular Weight 590.96
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Formula C38H70O4
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Color Colorless to light yellow
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SMILES
CCCCCC/C=C\CCCCCCCC(O[C@H](C)[C@H](C)OC(CCCCCCCCC/C=C/CCCCCC)=O)=O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
Ethanol : ≥ 100 mg/mL (169.22 mM)
THF : 40 mg/mL (67.69 mM; Need ultrasonic)
DMSO : 2 mg/mL (3.38 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Hu AJ, et al., Ultrasound assisted supercritical fluid extraction of oil and coixenolide from adlay seed. Ultrason Sonochem. 2007 Feb;14(2):219-24. [Content Brief]
[2]. Zhou, H., et al., (2014). Improved polysaccharide production in submerged culture of Ganoderma lucidum by the addition of coixenolide. Applied biochemistry and biotechnology, 172(3), 1497–1505. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / THF / Ethanol | 1 mM | 1.6922 mL | 8.4608 mL | 16.9216 mL | 42.3040 mL |
| THF / Ethanol | 5 mM | 0.3384 mL | 1.6922 mL | 3.3843 mL | 8.4608 mL |
| 10 mM | 0.1692 mL | 0.8461 mL | 1.6922 mL | 4.2304 mL | |
| 15 mM | 0.1128 mL | 0.5641 mL | 1.1281 mL | 2.8203 mL | |
| 20 mM | 0.0846 mL | 0.4230 mL | 0.8461 mL | 2.1152 mL | |
| 25 mM | 0.0677 mL | 0.3384 mL | 0.6769 mL | 1.6922 mL | |
| 30 mM | 0.0564 mL | 0.2820 mL | 0.5641 mL | 1.4101 mL | |
| 40 mM | 0.0423 mL | 0.2115 mL | 0.4230 mL | 1.0576 mL | |
| 50 mM | 0.0338 mL | 0.1692 mL | 0.3384 mL | 0.8461 mL | |
| 60 mM | 0.0282 mL | 0.1410 mL | 0.2820 mL | 0.7051 mL | |
| Ethanol | 80 mM | 0.0212 mL | 0.1058 mL | 0.2115 mL | 0.5288 mL |
| 100 mM | 0.0169 mL | 0.0846 mL | 0.1692 mL | 0.4230 mL |
Coixenolide Related Classifications
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