Ulicyclamide
Ulicyclamide is a cytotoxic cyclic peptide found in the tunicate Lissoclinum patella.Ulicyclamide inhibits DNA and RNA synthesis in leukemia cells. Ulicyclamide can be used for the research of leukemia.
For research use only. We do not sell to patients.
- CAS No.: 74839-81-9
- Formula: C33H39N7O5S2
- Molecular Weight:677.84
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All DNA/RNA Synthesis Isoforms
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Biological Activity
Ulicyclamide (dose-response curve range; 48 h) is cytotoxic against cultured L1210 mouse leukemia cells in vitro, with an IC50 of 13 μg/mL after 48 h of incubation[1].
Ulicyclamide (dose-response curve range; 2 h) potently inhibits both DNA and RNA syntheses (IC50 = 2.2 μg/mL for each) in cultured L1210 mouse leukemia cells after 2 hr of incubation, while having no effect on protein synthesis[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 74839-81-9
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Molecular Weight 677.84
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Formula C33H39N7O5S2
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SMILES
O=C(N1CCC[C@]1(C2=N[C@]([H])3[C@H](O2)C)[H])[C@@H](NC(C4=CSC([C@H](NC(C5=CSC([C@@H](NC3=O)[C@@H](C)CC)=N5)=O)C)=N4)=O)CC6=CC=CC=C6
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Ulicyclamide Related Classifications
HY-182258 Related Classifications
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