Asciminib-d4
Asciminib-d4 (ABL001-d4) is the deuterated-labeled Asciminib (HY-104010). Asciminib (ABL001) is a potent and selective allosteric BCR-ABL1 inhibitor, which inhibits Ba/F3 cells grown with an IC50 of 0.25 nM.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Fòrmula: C20H14D4ClF2N5O3
- Peso molecular:453.86
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
- Pureza y Documentación
- Referencias
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Help & FAQs
Actividad biológica
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 1492952-76-7
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Peso molecular 453.86
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Fòrmula C20H14D4ClF2N5O3
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SMILES
O=C(NC1=CC=C(OC(F)(Cl)F)C=C1)C2=CN=C(N3C([2H])([2H])[C@H](O)CC3([2H])[2H])C(C4=CC=NN4)=C2
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Synonyms
ABL001-d4
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Asciminib-d4 Related Classifications
HY-104010S Related Classifications
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