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Referencia número: HY-49537

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ER ligand-10

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Based on 1 Customer Validation

ER ligand-10 (Compound 11a) is a weak ERa and ERβ ligand, and shows weak estrogenic activity.

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No. CAS: 1075742-56-1
Fòrmula: C₁₄H₁₃NO₃
Peso molecular:243.26

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

ER ligand-10 Chemical Structure

No. CAS: 1075742-56-1

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Actividad biológica
- Descripciòn
- Cellular Effect
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
Bioz

Actividad biológica

Descripciòn

ER ligand-10 (Compound 11a) is a weak ERa and ERβ ligand, and shows weak estrogenic activity^[1].

Ver todos los productos específicos de isoformas Estrogen Receptor/ERR :

Cellular Effect

Cell Line	Type	Value	Description	References
MCF7	EC₅₀	4.3 x 10^-5 M Compound: 11a	Estrogenic activity in human MCF7 cells assessed as cell proliferation after 6 days by WST8 assay Estrogenic activity in human MCF7 cells assessed as cell proliferation after 6 days by WST8 assay	[PMID: 18760603]
MCF7	EC₅₀	43 μM Compound: 11a	Estrogenic activity in human MCF7 cells assessed as cell proliferation after 6 days by WST8 assay Estrogenic activity in human MCF7 cells assessed as cell proliferation after 6 days by WST8 assay	[PMID: 18760603]

Chemical Information

No. CAS 1075742-56-1
Peso molecular 243.26
Fòrmula C₁₄H₁₃NO₃
SMILES

CC(N(C1=CC=C(O)C=C1)C2=CC=C(O)C=C2)=O
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Ohta K, et al. Promising core structure for nuclear receptor ligands: design and synthesis of novel estrogen receptor ligands based on diphenylamine skeleton. Bioorg Med Chem Lett. 2008 Sep 15;18(18):5050-3. [Content Brief]

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Calculadora de dilución

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Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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ER ligand-10

High-Throughput Bioactive Compound Library

Ver todos los productos específicos de isoformas Estrogen Receptor/ERR

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

ER ligand-10 Related Classifications

HY-49537 Related Classifications