Tovecimig
Based on 1 Customer Validation
HY-P991033 is an VEGFA/DLL4-targeting G1-scFvlh_L-κ type bispecific antibody.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza: 97.39%
- No. CAS: 2923284-73-3
- Peso molecular:199.624 kDa
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Ver todos los productos específicos de isoformas VEGFR
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Actividad biológica
IgG1-kappa-[scFv]2-lambda-heavy
Human
VEGFA & DLL4
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
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IgG1-kappa-[scFv]2-lambda-heavy
ELISA, FACS, Functional assay
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Immobilized VEGF121 Protein, Human (120 a.a, HY-P7420) can bind Tovecimig. The EC50 for this effect is 10.9 ng/mL. -
Immobilized Delta-like protein 4/DLL4 Protein, Human (HEK293, HY-P72972) can bind Tovecimig. The EC50 for this effect is 16.06 ng/mL. -
Flow cytometric analysis of 1X106 HeLa cells with Tovecimig (HY-P991033, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control.
Chemical Information
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No. CAS 2923284-73-3
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Appearance Liquid
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Peso molecular 199.624 kDa
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Color Colorless to light yellow
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SMILES
[Tovecimig]
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Synonyms
CTX-009
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Envío
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
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Ficha de datos (254 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)