Lrrc8c - leucine rich repeat containing 8 family, member C Gene

Also Known as AD158; fad158; E430036I04Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 100604

Summary

Contributes to volume-sensitive anion channel activity. Involved in anion transmembrane transport and protein hexamerization. Acts upstream of or within fat cell differentiation. Located in endoplasmic reticulum. Is integral component of plasma membrane. Part of ion channel complex. Is expressed in retina. Orthologous to human LRRC8C (leucine rich repeat containing 8 VRAC subunit C). [provided by Alliance of Genome Resources, Apr 2022]

Lrrc8c Products (1)

mRNA Protein Name
NM_133897.2 NP_598658.1 volume-regulated anion channel subunit LRRC8C

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
contributes to volume-sensitive anion channel activity IMP
IMP: Inferred from mutant phenotype
29769723 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within fat cell differentiation IDA
IDA: Inferred from direct assay
15184384 MGI
acts upstream of or within fat cell differentiation IMP
IMP: Inferred from mutant phenotype
15184384 MGI
involved in monoatomic anion transmembrane transport IMP
IMP: Inferred from mutant phenotype
29769723 MGI
involved in protein hexamerization IDA
IDA: Inferred from direct assay
29769723 MGI
Cellular Component GO Annotation Evidence References Source
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
15184384 MGI
part of monoatomic ion channel complex IMP
IMP: Inferred from mutant phenotype
29769723 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

volume-regulated anion channel subunit LRRC8C

  • factor for adipocyte differentiation 158

  • leucine-rich repeat-containing protein 8C

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07829 LRRC8C Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lrrc8c NCBI NCBI:84230