Pwp1 - PWP1 homolog, endonuclein Gene

Also Known as 2310058A11Rik; 2610205J09Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 103136

Summary

Enables H4K20me3 modified histone binding activity. Acts upstream of or within histone H4-K20 trimethylation; negative regulation of peptidyl-serine phosphorylation of STAT protein; and positive regulation of stem cell differentiation. Located in nucleus. Is expressed in several structures, including brain; neural retina; and trachea. Orthologous to human PWP1 (PWP1 homolog, endonuclein). [provided by Alliance of Genome Resources, Apr 2022]

Pwp1 Products (1)

mRNA Protein Name
NM_133993.3 NP_598754.2 periodic tryptophan protein 1 homolog

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables H4K20me3 modified histone binding IDA
IDA: Inferred from direct assay
25335925 MGI
enables histone chaperone activity IMP
IMP: Inferred from mutant phenotype
25335925 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of peptidyl-serine phosphorylation of STAT protein IMP
IMP: Inferred from mutant phenotype
25335925 MGI
acts upstream of or within positive regulation of stem cell differentiation IMP
IMP: Inferred from mutant phenotype
25335925 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
25335925 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

periodic tryptophan protein 1 homolog

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11475 PWP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pwp1 NCBI NCBI:11137