2. Gene
  3. Mtbp - Mdm2, transformed 3T3 cell double minute p53 binding protein Gene

Mtbp - Mdm2, transformed 3T3 cell double minute p53 binding protein Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as MDM2BP

Gene ID: 105837 | Gene type: protein coding

About Mtbp

Summary

Acts upstream of or within negative regulation of cell population proliferation; negative regulation of mitotic nuclear division; and traversing start control point of mitotic cell cycle. Located in kinetochore. Is expressed in cerebellum; midbrain ventricular layer; olfactory cortex ventricular layer; and telencephalon ventricular layer. Orthologous to human MTBP (MDM2 binding protein). [provided by Alliance of Genome Resources, Apr 2022]

Mtbp Products(2)

mRNA Protein Name
NM_001168250.1 NP_001161722.1 mdm2-binding protein isoform 2
NM_134092.3 NP_598853.3 mdm2-binding protein isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
10906133 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within negative regulation of cell population proliferation IDA
IDA: Inferred from direct assay
10906133 MGI
acts upstream of or within negative regulation of mitotic nuclear division IDA
IDA: Inferred from direct assay
21274008 MGI
acts upstream of or within traversing start control point of mitotic cell cycle IDA
IDA: Inferred from direct assay
10906133 MGI
Cellular Component GO Annotation Evidence Reference Source
located in kinetochore IDA
IDA: Inferred from direct assay
21274008 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mdm2-binding protein

mMTBP

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08753 MTBP Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mtbp NCBI NCBI:27085