Pacs1 - phosphofurin acidic cluster sorting protein 1 Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 107975

Summary

Predicted to enable transmembrane transporter binding activity. Acts upstream of or within protein localization to Golgi apparatus. Located in COPI-coated vesicle. Is expressed in nervous system. Human ortholog(s) of this gene implicated in Schuurs-Hoeijmakers Syndrome. Orthologous to human PACS1 (phosphofurin acidic cluster sorting protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Pacs1 Products (6)

mRNA Protein Name
NM_001362451.3 NP_001349380.1 phosphofurin acidic cluster sorting protein 1 isoform 2
NM_001403566.1 NP_001390495.1 phosphofurin acidic cluster sorting protein 1 isoform 4
NM_001403567.1 NP_001390496.1 phosphofurin acidic cluster sorting protein 1 isoform 3
NM_001403568.1 NP_001390497.1 phosphofurin acidic cluster sorting protein 1 isoform 5
NM_001403569.1 NP_001390498.1 phosphofurin acidic cluster sorting protein 1 isoform 6
NM_153129.4 NP_694769.2 phosphofurin acidic cluster sorting protein 1 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
33630350 MGI
Biological Process GO Annotation Evidence References Source
involved in lymphocyte homeostasis IMP
IMP: Inferred from mutant phenotype
33630350 MGI
acts upstream of or within protein localization to Golgi apparatus IDA
IDA: Inferred from direct assay
9695949 MGI
Cellular Component GO Annotation Evidence References Source
located in COPI-coated vesicle IDA
IDA: Inferred from direct assay
9695949 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

phosphofurin acidic cluster sorting protein 1

  • cytosolic sorting protein PACS-1

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-13523 PAC-1 99.88% Phase 2
Bioactive MoleculesInhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P99509 Zelminemab Inhibitor 98.79% Phase 2

Pre-clinical Phase

Bioactive Molecules (15)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P0221 PACAP (1-38), human, ovine, rat Inducer 99.99% Unkown
HY-P0176 PACAP (1-27), human, ovine, rat 99.30% Unkown
HY-P0221C PACAP (1-38) free acid 99.94% Unkown
HY-133529 PA-8 97.00% Unkown
HY-147557 PA-915 Antagonist 99.17% Unkown
HY-P0176A PACAP (1-27), human, ovine, rat TFA 99.81% Unkown
HY-129421 PA-9 99.73% Unkown
HY-159632 PAR4 antagonist 6 Antagonist 99.35% Unkown
HY-160694 cBu-Cit-GAL-02-221 Degrader / Unkown
HY-129937 (S)-GNE-987 Inhibitor / Unkown
HY-13523S PAC-1-d8 / Unkown
HY-P0221A PACAP (1-38), human, ovine, rat TFA Inducer / Unkown
HY-P3483 Maxadilan / Unkown
HY-RS09955 PACS1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-119158 VU0652925 / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pacs1 NCBI NCBI:55690