Sp110 - Sp110 nuclear body protein Gene

Also Known as Ipr1; 52kDa; Ifi75; 5031415C07Rik; 5830484A20Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 109032

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Acts upstream of or within positive regulation of apoptotic process and response to bacterium. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in genitourinary system and thymus primordium. Human ortholog(s) of this gene implicated in hepatic venoocclusive disease with immunodeficiency and tuberculosis. Orthologous to human SP110 (SP110 nuclear body protein). [provided by Alliance of Genome Resources, Apr 2022]

Sp110 Products (2)

mRNA Protein Name
NM_030194.1 NP_084470.1 sp110 nuclear body protein
NM_175397.4 NP_780606.3 sp110 nuclear body protein

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within positive regulation of apoptotic process IDA
IDA: Inferred from direct assay
15815631 MGI
acts upstream of or within response to bacterium IDA
IDA: Inferred from direct assay
15815631 MGI
acts upstream of or within response to bacterium IEP
IEP: Inferred from expression pattern
23012479 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sp110 nuclear body protein

  • interferon-induced protein 75, 52kD

  • intracellular pathogen resistance 1

  • intracellular pathogen resistance protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10769 PMP22 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS13602 SP110 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22816 Sp110 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29331 Sp110 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sp110 NCBI NCBI:3431