Arhgef28 - Rho guanine nucleotide exchange factor (GEF) 28 Gene

Also Known as RIP2; Rgnef; RhoGEF; Rhoip2; p190RhoGEF; D13Bwg1089e; 9230110L08Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 110596

Summary

Predicted to enable guanyl-nucleotide exchange factor activity. Acts upstream of or within central nervous system neuron axonogenesis and neurofilament Cytoskeleton organization. Predicted to be located in cytoplasm and plasma membrane. Is expressed in adrenal gland; genitourinary system; oral epithelium; paravertebral ganglion; and stomach. Orthologous to human ARHGEF28 (Rho guanine nucleotide exchange factor 28). [provided by Alliance of Genome Resources, Apr 2022]

Arhgef28 Products (5)

mRNA Protein Name
NM_001408684.1 NP_001395613.1 rho guanine nucleotide exchange factor 28 isoform 2
NM_001408685.1 NP_001395614.1 rho guanine nucleotide exchange factor 28 isoform 3
NM_001408686.1 NP_001395615.1 rho guanine nucleotide exchange factor 28 isoform 4
NM_001408687.1 NP_001395616.1 rho guanine nucleotide exchange factor 28 isoform 5
NM_012026.3 NP_036156.2 rho guanine nucleotide exchange factor 28 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
16236762 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within central nervous system neuron axonogenesis IMP
IMP: Inferred from mutant phenotype
15378065 MGI
acts upstream of or within neurofilament cytoskeleton organization IMP
IMP: Inferred from mutant phenotype
16236762 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

rho guanine nucleotide exchange factor 28

  • 190 kDa guanine nucleotide exchange factor

  • Rho interacting protein 2

  • Rho specific exchange factor

  • Rho-guanine nucleotide exchange factor

  • p190-RhoGEF

  • rho-interacting protein 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00957 ARHGEF28 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Arhgef28 NCBI NCBI:64283