Lrrtm3 - leucine rich repeat transmembrane neuronal 3 Gene

Also Known as 9630044H04Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 216028

Summary

Acts upstream of or within positive regulation of amyloid-beta formation and positive regulation of synapse assembly. Located in glutamatergic synapse. Is integral component of postsynaptic density membrane. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; future brain; and male reproductive gland or organ. Orthologous to human LRRTM3 (leucine rich repeat transmembrane neuronal 3). [provided by Alliance of Genome Resources, Apr 2022]

Lrrtm3 Products (1)

mRNA Protein Name
NM_178678.4 NP_848793.1 leucine-rich repeat transmembrane neuronal protein 3 precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within positive regulation of amyloid-beta formation IMP
IMP: Inferred from mutant phenotype
17098871 MGI
acts upstream of or within positive regulation of synapse assembly IDA
IDA: Inferred from direct assay
24613359 MGI
Cellular Component GO Annotation Evidence References Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
26776509 MGI
is active in glutamatergic synapse IEP
IEP: Inferred from expression pattern
26776509 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
26776509 MGI
is active in postsynaptic density membrane IDA
IDA: Inferred from direct assay
26776509 MGI
is active in postsynaptic density membrane IEP
IEP: Inferred from expression pattern
26776509 MGI
is active in postsynaptic density membrane IMP
IMP: Inferred from mutant phenotype
26776509 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

leucine-rich repeat transmembrane neuronal protein 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07843 LRRTM3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18711 Lrrtm3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25198 Lrrtm3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lrrtm3 NCBI NCBI:347731