LRRTM3 - leucine rich repeat transmembrane neuronal 3 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 347731

About LRRTM3

Cytogenetic location: 10q21.3 Genomic coordinates (GRCh38): 10:66,926,036-67,101,551 (from NCBI)

This gene has 3 transcripts (splice variants), 130 orthologues and 22 paralogues. Biased expression in brain (RPKM 4.5), adrenal (RPKM 1.0) and 2 other tissues.

Summary

Involved in presynapse assembly. Acts upstream of or within positive regulation of amyloid-beta formation. Is active in glutamatergic synapse. [provided by Alliance of Genome Resources, Apr 2022]

LRRTM3 Products (1)

mRNA Protein Name
NM_178011.5 NP_821079.3 leucine-rich repeat transmembrane neuronal protein 3 precursor

LRRTM3 Protein Structure

LRRNT

LRRNT: Leucine rich repeat N-terminal domain (33 - 58)

LRR_8

LRR_8: Leucine rich repeat (66 - 121)

LRR_6

LRR_6: Leucine Rich repeat (133 - 150)

LRR_8

LRR_8: Leucine rich repeat (161 - 216)

LRR_8

LRR_8: Leucine rich repeat (230 - 290)

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  • 581 a.a.
Protein Preferred Names Protein Names

leucine-rich repeat transmembrane neuronal protein 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07843 LRRTM3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18711 Lrrtm3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25198 Lrrtm3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta LRRTM3 VGNC VGNC:74316
Felis catus LRRTM3 VGNC VGNC:63316
Canis familiaris LRRTM3 VGNC VGNC:42831
Rattus norvegicus LRRTM3 RGD RGD:1304866
Mus musculus LRRTM3 MGD MGI:2389177
Bos taurus LRRTM3 VGNC VGNC:31044
Others LRRTM3 NCBI