Tenm3 - teneurin transmembrane protein 3 Gene

Mus musculus

Also known as Odz1; Odz3; Ten-m3; mKIAA1455; 2610100B16Rik

Gene ID: 23965 | Gene type: protein coding

About Tenm3

Summary

Enables protein heterodimerization activity and protein homodimerization activity. Involved in homophilic cell adhesion via plasma membrane adhesion molecules; positive regulation of neuron projection development; and regulation of homophilic cell adhesion. Located in membrane. Is integral component of plasma membrane. Is expressed in several structures, including alimentary system; branchial arch; genitourinary system; nervous system; and sensory organ. Orthologous to human TENM3 (teneurin transmembrane protein 3). [provided by Alliance of Genome Resources, Apr 2022]

Tenm3 Products(2)

mRNA	Protein	Name
NM_001145937.1	NP_001139409.1	teneurin-3 isoform 2
NM_011857.3	NP_035987.3	teneurin-3 isoform 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables identical protein binding	IPI IPI: Inferred from physical interaction	12000766	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	12000766	MGI
enables protein heterodimerization activity	IDA IDA: Inferred from direct assay	12000766	MGI
NOT enables protein homodimerization activity	IDA IDA: Inferred from direct assay	29414938	MGI
enables protein homodimerization activity	IDA IDA: Inferred from direct assay	12000766	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in homophilic cell adhesion via plasma membrane adhesion molecules	IDA IDA: Inferred from direct assay	17478416	MGI
involved in positive regulation of neuron projection development	IDA IDA: Inferred from direct assay	17478416	MGI
involved in positive regulation of neuron projection development	IMP IMP: Inferred from mutant phenotype	17803360	MGI
NOT involved in regulation of homophilic cell adhesion	IDA IDA: Inferred from direct assay	29414938	MGI
involved in regulation of homophilic cell adhesion	IDA IDA: Inferred from direct assay	29414938	MGI
involved in synaptic membrane adhesion	IDA IDA: Inferred from direct assay	35484136	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
is active in glutamatergic synapse	IDA IDA: Inferred from direct assay	35484136	MGI
located in membrane	IDA IDA: Inferred from direct assay	17478416	MGI
located in plasma membrane	IDA IDA: Inferred from direct assay	29414938	MGI
is active in presynaptic active zone membrane	IDA IDA: Inferred from direct assay	35484136	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

teneurin-3

odd Oz/ten-m homolog 3	protein Odd Oz/ten-m homolog 3
ten-3	tenascin-M3

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14364	TENM3 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Tenm3	NCBI	NCBI:55714

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