Tnfaip8l3 - tumor necrosis factor, alpha-induced protein 8-like 3 Gene
Also Known as Gm517; 9930029P06Rik
Species: Mus musculus
Summary
Enables phosphatidylinositol binding activity and phosphatidylinositol transfer activity. Involved in several processes, including inositol lipid-mediated signaling; positive regulation of intracellular signal transduction; and positive regulation of phosphatidylinositol 3-kinase activity. Located in cytoplasm and plasma membrane. Orthologous to human TNFAIP8L3 (TNF alpha induced protein 8 like 3). [provided by Alliance of Genome Resources, Apr 2022]
Tnfaip8l3 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_001033535.3 | NP_001028707.1 | tumor necrosis factor alpha-induced protein 8-like protein 3 |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables phosphatidylinositol binding |
IDA
IDA: Inferred from direct assay
|
25242044 | MGI |
| enables phosphatidylinositol transfer activity |
IMP
IMP: Inferred from mutant phenotype
|
25242044 | MGI |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| involved in 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate metabolic process |
IDA
IDA: Inferred from direct assay
|
25242044 | MGI |
| involved in phospholipid transport |
IDA
IDA: Inferred from direct assay
|
25242044 | MGI |
| involved in positive regulation of ERK1 and ERK2 cascade |
IDA
IDA: Inferred from direct assay
|
25242044 | MGI |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| located in cytoplasm |
IDA
IDA: Inferred from direct assay
|
25479791 | MGI |
| located in plasma membrane |
IDA
IDA: Inferred from direct assay
|
25242044 | MGI |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
tumor necrosis factor alpha-induced protein 8-like protein 3 |
|
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