TNFAIP8L3 - TNF alpha induced protein 8 like 3 Gene

Also Known as TIPE3

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 388121

About TNFAIP8L3

Cytogenetic location: 15q21.2 Genomic coordinates (GRCh38): 15:51,056,601-51,105,276 (from NCBI)

This gene has 3 transcripts (splice variants), 208 orthologues and 3 paralogues. Broad expression in endometrium (RPKM 16.6), esophagus (RPKM 6.5) and 15 other tissues.

Summary

Predicted to enable phosphatidylinositol binding activity and phosphatidylinositol transfer activity. Predicted to be involved in several processes, including inositol lipid-mediated signaling; positive regulation of intracellular signal transduction; and positive regulation of phosphatidylinositol 3-kinase activity. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

TNFAIP8L3 Products (2)

mRNA Protein Name
NM_001311175.2 NP_001298104.1 tumor necrosis factor alpha-induced protein 8-like protein 3 isoform 2
NM_207381.4 NP_997264.2 tumor necrosis factor alpha-induced protein 8-like protein 3 isoform 1

TNFAIP8L3 Protein Structure

DUF758

DUF758: Domain of unknown function (DUF758) (108 - 291)

  • 0
  • 100
  • 200
  • 292 a.a.
Protein Preferred Names Protein Names

tumor necrosis factor alpha-induced protein 8-like protein 3

  • TNF alpha-induced protein 8-like protein 3

TNFAIP8L3 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
TNFAIP8L3 Q5GJ75 CBY1 Homo sapiens Q9Y3M2
Validated Y2H
32296183
Intra
TNFAIP8L3 Q5GJ75 CBY1 Homo sapiens Q9Y3M2
Y2H Prey Pooling
32296183
Intra
TNFAIP8L3 Q5GJ75 CBY1 Homo sapiens Q9Y3M2
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Astigmatism
Colon Mucinous Adenocarcinoma

  • Colonic Mucinous Adenocarcinoma

  • Mucinous Adenocarcinoma Of The Colon
Hereditary Spastic Paraplegia 51

  • Autosomal Dominant Spastic Paraplegia 51

  • Cpsq4

  • Spastic Quadriplegic Cerebral Palsy 4

  • Spg51

  • Spastic Paraplegia 51, Autosomal Recessive
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14794 TNFAIP8L3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus TNFAIP8L3 VGNC VGNC:36160
Mus musculus TNFAIP8L3 MGD MGI:2685363
Macaca mulatta TNFAIP8L3 VGNC VGNC:79260
Rattus norvegicus TNFAIP8L3 RGD RGD:1311533
Canis familiaris TNFAIP8L3 VGNC VGNC:49759
Felis catus TNFAIP8L3 VGNC VGNC:80816
Others TNFAIP8L3 NCBI