Ddn - dendrin Gene

Rattus norvegicus

Also known as Den

Gene ID: 25113 | Gene type: protein coding

About Ddn

Summary

Enables DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Located in dendrite. Orthologous to human DDN (dendrin). [provided by Alliance of Genome Resources, Apr 2022]

Ddn Products(1)

mRNA	Protein	Name
NM_030993.2	NP_112255.1	dendrin

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IDA IDA: Inferred from direct assay	21911934	RGD
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA IDA: Inferred from direct assay	21911934	RGD
enables protein binding	IPI IPI: Inferred from physical interaction	16464232	RGD

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within positive regulation of transcription by RNA polymerase II	IDA IDA: Inferred from direct assay	21911934	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in dendrite	IDA IDA: Inferred from direct assay	9073398	RGD
is active in postsynapse	IDA IDA: Inferred from direct assay	33524899	RGD
is active in presynapse	IDA IDA: Inferred from direct assay	33524899	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

dendrin

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-138842	DDN	Activator	/	Unkown
HY-RS03617	DDN Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-W744266	9α,10α-Epoxyhexahydrocannabinol		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Ddn	NCBI	NCBI:23109

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