Map3k12 - mitogen activated protein kinase kinase kinase 12 Gene

Also Known as PK; DLK; MUK; Zpk

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25579

Summary

Predicted to enable JUN kinase kinase kinase activity; protein homodimerization activity; and protein kinase binding activity. Predicted to be involved in several processes, including JNK cascade; positive regulation of MAPK cascade; and protein phosphorylation. Predicted to act upstream of or within negative regulation of motor neuron apoptotic process. Predicted to be located in cytosol; growth cone; and plasma membrane. Orthologous to human MAP3K12 (mitogen-activated protein kinase kinase kinase 12). [provided by Alliance of Genome Resources, Apr 2022]

Map3k12 Products (1)

mRNA Protein Name
NM_013055.1 NP_037187.1 mitogen-activated protein kinase kinase kinase 12
Protein Preferred Names Protein Names

mitogen-activated protein kinase kinase kinase 12

  • MAPK-upstream kinase

  • Mitogen activated protein kinase 12 (Zipper (leucine) protein kinase)

  • Zipper (leucine) protein kinase

  • dual leucine zipper bearing kinase

  • dual leucine zipper kinase

  • leucine-zipper protein kinase

  • mixed lineage kinase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-114331 DLK-IN-1 Inhibitor 98.27% Unkown
HY-170484 KAI-11101 Inhibitor / Unkown
HY-RS08049 MAP3K12 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Map3k12 NCBI NCBI:7786