Map3k12 - mitogen activated protein kinase kinase kinase 12 Gene

Rattus norvegicus

Also known as PK; DLK; MUK; Zpk

Gene ID: 25579 | Gene type: protein coding

About Map3k12

Summary

Predicted to enable JUN kinase kinase kinase activity; protein homodimerization activity; and protein kinase binding activity. Predicted to be involved in several processes, including JNK cascade; positive regulation of MAPK cascade; and protein phosphorylation. Predicted to act upstream of or within negative regulation of motor neuron apoptotic process. Predicted to be located in cytosol; growth cone; and plasma membrane. Orthologous to human MAP3K12 (mitogen-activated protein kinase kinase kinase 12). [provided by Alliance of Genome Resources, Apr 2022]

Map3k12 Products(1)

mRNA	Protein	Name
NM_013055.1	NP_037187.1	mitogen-activated protein kinase kinase kinase 12

Protein Preferred Names

Protein Names

mitogen-activated protein kinase kinase kinase 12

MAPK-upstream kinase	Mitogen activated protein kinase 12 (Zipper (leucine) protein kinase)
Zipper (leucine) protein kinase	dual leucine zipper bearing kinase
dual leucine zipper kinase	leucine-zipper protein kinase
mixed lineage kinase

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-114331	DLK-IN-1	Inhibitor	98.27%	Unkown
HY-170484	KAI-11101	Inhibitor	/	Unkown
HY-RS08049	MAP3K12 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Map3k12	NCBI	NCBI:7786

Name
Email *

	Sorry, but the email address you supplied was invalid.