Kcnq5 - potassium voltage-gated channel subfamily Q member 5 Gene

Also Known as Kcnq5l

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 259273

Summary

Enables voltage-gated Potassium Channel activity. Involved in potassium ion transport. Predicted to be integral component of plasma membrane. Predicted to be part of clathrin coat and voltage-gated Potassium Channel complex. Predicted to be integral component of membrane. Human ortholog(s) of this gene implicated in autosomal dominant mental retardation 46. Orthologous to human KCNQ5 (potassium voltage-gated channel subfamily Q member 5). [provided by Alliance of Genome Resources, Apr 2022]

Kcnq5 Products (1)

mRNA Protein Name
NM_001134643.2 NP_001128115.2 potassium voltage-gated channel subfamily KQT member 5

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential EXP
EXP: Inferred from Experiment
21666672 RGD
enables voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential IDA
IDA: Inferred from direct assay
21666672 RGD
enables voltage-gated potassium channel activity IMP
IMP: Inferred from mutant phenotype
12032157 RGD
Biological Process GO Annotation Evidence References Source
involved in potassium ion transport IMP
IMP: Inferred from mutant phenotype
12032157 RGD
Cellular Component GO Annotation Evidence References Source
is active in calyx of Held EXP
EXP: Inferred from Experiment
21666672 RGD
is active in calyx of Held IDA
IDA: Inferred from direct assay
17912742 RGD
is active in presynaptic membrane IDA
IDA: Inferred from direct assay
17912742 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

potassium voltage-gated channel subfamily KQT member 5

  • potassium channel, voltage-gated KQT-like subfamily Q, member 5

  • potassium voltage-gated channel, KQT-like subfamily, member 5

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-123264 RL648_81 Inhibitor 99.49% Unkown
HY-182435 CLE-030 Agonist / Unkown
HY-RS07177 KCNQ5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20973 Kcnq5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27490 Kcnq5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kcnq5 NCBI NCBI:56479