Fam107a - family with sequence similarity 107, member A Gene

Mus musculus

Also known as DRR1

Gene ID: 268709 | Gene type: protein coding

About Fam107a

Summary

Predicted to enable actin binding activity. Involved in several processes, including actin filament organization; cellular response to glucocorticoid stimulus; and negative regulation of long-term synaptic potentiation. Located in actin cytoskeleton; neuron projection; and synapse. Is expressed in diencephalon ventricular layer; hypothalamus ventricular layer; inner ear; and olfactory epithelium. Orthologous to human FAM107A (family with sequence similarity 107 member A). [provided by Alliance of Genome Resources, Apr 2022]

Fam107a Products(4)

mRNA	Protein	Name
NM_001360337.1	NP_001347266.1	actin-associated protein FAM107A isoform 1
NM_001360338.1	NP_001347267.1	actin-associated protein FAM107A isoform 1
NM_001360339.1	NP_001347268.1	actin-associated protein FAM107A isoform 2
NM_183187.4	NP_899010.1	actin-associated protein FAM107A isoform 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	21969592	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in actin filament bundle assembly	IMP IMP: Inferred from mutant phenotype	21969592	MGI
involved in actin filament polymerization	IMP IMP: Inferred from mutant phenotype	21969592	MGI
involved in cellular response to glucocorticoid stimulus	IMP IMP: Inferred from mutant phenotype	21969592	MGI
involved in cellular response to nutrient levels	IMP IMP: Inferred from mutant phenotype	21969592	MGI
involved in cognition	IMP IMP: Inferred from mutant phenotype	21969592	MGI
involved in negative regulation of long-term synaptic potentiation	IMP IMP: Inferred from mutant phenotype	21969592	MGI
involved in regulation of postsynapse assembly	IDA IDA: Inferred from direct assay	21969592	MGI
involved in regulation of postsynapse assembly	IMP IMP: Inferred from mutant phenotype	21969592	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in actin cytoskeleton	IDA IDA: Inferred from direct assay	21969592	MGI
is active in glutamatergic synapse	IDA IDA: Inferred from direct assay	21969592	MGI
is active in glutamatergic synapse	IMP IMP: Inferred from mutant phenotype	21969592	MGI
located in neuron projection	IDA IDA: Inferred from direct assay	20298674	MGI
is active in postsynaptic actin cytoskeleton	IDA IDA: Inferred from direct assay	21969592	MGI
is active in presynaptic actin cytoskeleton	IDA IDA: Inferred from direct assay	21969592	MGI
located in synapse	IDA IDA: Inferred from direct assay	21969592	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

actin-associated protein FAM107A

protein FAM107A

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04676	FAM107A Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Fam107a	NCBI	NCBI:11170

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