Stk36 - serine/threonine kinase 36 Gene

Predicted to enable protein serine/threonine kinase activity. Involved in several processes, including cilium assembly; positive regulation of hh target transcription factor activity; and positive regulation of smoothened signaling pathway. Acts upstream of or within brain development and epithelial cilium movement involved in extracellular fluid movement. Located in cytoplasm. Is expressed in several structures, including central nervous system; sensory organ; skeleton; tail somite; and testis. Used to study hydrocephalus. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia. Orthologous to human STK36 (serine/threonine kinase 36). [provided by Alliance of Genome Resources, Apr 2022]