Aoah - acyloxyacyl hydrolase Gene

Also Known as 4930433E13Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 27052

Summary

This genes encodes an enzyme that catalyzes the hydrolysis of acyloxylacyl-linked fatty acyl chains from Bacterial lipopolysaccharides. The encoded protein modulates host inflammatory response to gram-negative bacteria. The proprotein is further cleaved into a large and small chain that interact in a heterodimer. Alternative splicing results in multiple transcript variants for this gene. [provided by RefSeq, Aug 2013]

Aoah Products (2)

mRNA Protein Name
NM_001281854.1 NP_001268783.1 acyloxyacyl hydrolase isoform 2 preproprotein
NM_012054.4 NP_036184.1 acyloxyacyl hydrolase isoform 1 preproprotein

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables acyloxyacyl hydrolase activity IDA
IDA: Inferred from direct assay
15155618 MGI
enables calcium ion binding IDA
IDA: Inferred from direct assay
29343645 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within lipopolysaccharide metabolic process IDA
IDA: Inferred from direct assay
15155618 MGI
acts upstream of or within negative regulation of inflammatory response IDA
IDA: Inferred from direct assay
15155618 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

acyloxyacyl hydrolase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00770 AOAH Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Aoah NCBI NCBI:313