2. Gene
  3. ADAMDEC1 - ADAM like decysin 1 Gene

ADAMDEC1 - ADAM like decysin 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as M12.219

Gene ID: 27299 | Gene type: protein coding

About ADAMDEC1

Cytogenetic location: 8p21.2 Genomic coordinates (GRCh38): 8:24,384,285-24,406,013 (from NCBI)

This gene has 4 transcripts (splice variants), 358 orthologues and 20 paralogues. Biased expression in small intestine (RPKM 233.3), colon (RPKM 104.6) and 4 other tissues.

Summary

This encoded protein is thought to be a secreted protein belonging to the disintegrin metalloproteinase family. Its expression is upregulated during dendritic cells maturation. This protein may play an important role in dendritic cell function and their interactions with germinal center T cells. [provided by RefSeq, Jul 2008]

ADAMDEC1 Products(3)

mRNA Protein Name
NM_001145271.2 NP_001138743.1 ADAM 1-Dec isoform 2
NM_001145272.2 NP_001138744.1 ADAM 1-Dec isoform 2
NM_014479.3 NP_055294.1 ADAM 1-Dec isoform 1 precursor

ADAMDEC1 Protein Structure

Pep_M12B_propep

Pep_M12B_propep: Reprolysin family propeptide (43 - 173)

Reprolysin

Reprolysin: Reprolysin (M12B) family zinc metalloprotease (218 - 412)

Disintegrin

Disintegrin: Disintegrin (429 - 461)

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  • 470 a.a.
Protein Preferred Names Protein Names

ADAM DEC1

ADAM-like protein decysin-1

Recombinant ADAMDEC1 Proteins

Cat. No. Product Name Accession Purity
HY-P7460 ADAMDEC1 Protein, Human (HEK293, His) O15204 (K206-E470) ≥95%

Related Diseases

Diseases Alias
Rosacea

Erythematotelangiectatic Rosacea

Papulopustular Rosacea

Phymatous Rosacea

Acne Roscea

Acne, Erythematosa

Granulomatous Rosacea

Ocular Rosacea

Acne Rosacea

Hypertrophic Rosacea
Inflammatory Bowel Disease

Inflammatory Bowel Diseases

Bowel Disease, Inflammatory
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00290 ADAMDEC1 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta ADAMDEC1 VGNC VGNC:69422
Canis familiaris ADAMDEC1 VGNC VGNC:37589
Felis catus ADAMDEC1 VGNC VGNC:59586
Mus musculus ADAMDEC1 MGD MGI:1917650
Rattus norvegicus ADAMDEC1 RGD RGD:1309861
Others ADAMDEC1 NCBI