Arhgef15 - Rho guanine nucleotide exchange factor 15 Gene

Rattus norvegicus

Also known as E5

Gene ID: 287418 | Gene type: protein coding

About Arhgef15

Summary

Enables guanyl-nucleotide exchange factor activity. Involved in positive regulation of stress fiber assembly and regulation of catalytic activity. Located in cytoplasm. Orthologous to human ARHGEF15 (Rho guanine nucleotide exchange factor 15). [provided by Alliance of Genome Resources, Apr 2022]

Arhgef15 Products(1)

mRNA	Protein	Name
NM_001414295.1	NP_001401224.1	rho guanine nucleotide exchange factor 15

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables guanyl-nucleotide exchange factor activity	IDA IDA: Inferred from direct assay	12775584	RGD
enables protein binding	IPI IPI: Inferred from physical interaction	12775584	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in positive regulation of stress fiber assembly	IDA IDA: Inferred from direct assay	12775584	RGD
involved in regulation of catalytic activity	IDA IDA: Inferred from direct assay	12775584	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in cytoplasm	IDA IDA: Inferred from direct assay	12775584	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

rho guanine nucleotide exchange factor 15

Rho guanine nucleotide exchange factor (GEF) 15

ephexin-5

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00950	ARHGEF15 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Arhgef15	NCBI	NCBI:22899

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